02-08-2013, 11:04 AM #1Registered User
- Join Date
- Jul 2011
Small-molecule drug drives cancer cells to suicide
Cancer researchers have pinned down a molecule that can kick-start the body’s own tumour-destroying systems, triggering cell death in cancerous but not healthy tissue in mice.
The molecule, TIC10, activates the gene for a protein called TRAIL (tumour-necrosis-factor-related apoptosis-inducing ligand), which has long been a target for cancer researchers looking for drugs that would avoid the debilitating effects of conventional therapies.
“TRAIL is a part of our immune system: all of us with functional immune systems use this molecule to keep tumours from forming or spreading, so boosting this will not be as toxic as chemotherapy,” says Wafik El-Deiry, an oncologist at Pennsylvania State University in Hershey and lead author of the study, which is published today in Science Translational Medicine1.
02-08-2013, 03:03 PM #2Registered User
- Join Date
- Nov 2008
I do hope this can work, as long as any side effects are not bad, or as bad as chemo. Anything to help defeat cancer would be a real life miracle to me.
Unless I have included a link, it is my opinion and only my opinion that I am expressing.
By Reader in forum Up to the MinuteReplies: 4Last Post: 11-26-2013, 09:02 PM
By wfgodot in forum Up to the MinuteReplies: 0Last Post: 05-17-2012, 08:41 AM
By Autumn2004 in forum Up to the MinuteReplies: 25Last Post: 07-15-2007, 04:25 PM