Linda7NJ
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Scientists win right to create human embryo with three genetic parents
First, an egg from a woman carrying mitochondrial defects will be fertilised in vitro using her partners sperm. At the point of fertilisation, two pronuclei containing genetic material from the mother and father will be removed, and injected into an unfertilised egg from which the nucleus has been removed.
This donated egg will contain healthy mitochondria, but none of the nuclear DNA that makes up most of the human genetic code.
But mitochondria contain 37 genes, so the embryo will have been created with a genetic contribution from three individuals the father, the mother who provided the nucleus, and the donor who provided the mitochondria. If the embryo grows into an adult woman, she would pass on the donated mitochondria to any children of her own, raising concerns about germ-line genetic manipulation.
link for more:
http://www.timesonline.co.uk/article/0,,2-1772135,00.html
First, an egg from a woman carrying mitochondrial defects will be fertilised in vitro using her partners sperm. At the point of fertilisation, two pronuclei containing genetic material from the mother and father will be removed, and injected into an unfertilised egg from which the nucleus has been removed.
This donated egg will contain healthy mitochondria, but none of the nuclear DNA that makes up most of the human genetic code.
But mitochondria contain 37 genes, so the embryo will have been created with a genetic contribution from three individuals the father, the mother who provided the nucleus, and the donor who provided the mitochondria. If the embryo grows into an adult woman, she would pass on the donated mitochondria to any children of her own, raising concerns about germ-line genetic manipulation.
link for more:
http://www.timesonline.co.uk/article/0,,2-1772135,00.html
