I have taken Xenical as part of a weight loss program. I took it for about 4.5 months. It does help in removing a percentage of the fat that you consume, but it has VERY undesirable, uncontrollable, embarrassing side effects that occur without warning. As part of the plan with taking Xenical, you aren't supposed to consume much in the way of fatty foods. If you do, Xenical keeps your system from absorbing the majority of the fat, "sending the fat out of your system"...if anyone wants more of a specific or graphic explanation, I'll be glad to provide, but I don't want to make anyone sick if no one wants to know.... In order to avoid the undesirable side effects that come with taking Xenical, you cut the fat...so if you are going to cut the fat anyway - you don't need Xenical - because you are cutting fat anyway. You can't just add Xenical to your diet and continue eating fatty foods, you have to reduce the amount of fatty foods that you take in. So I quit taking it. I found that while taking Xenical, I was reducing the fat to avoid the negative side effects, and I was doing that on my own - proving to myself that I actually CAN reduce the fat intake. So I continued my new habit of not consuming such fatty food - and losing weight all on my own. The side effects helped me to develop self control that I didn't know I had, in regards to my food choices. So, no matter whether it is prescription, or over the counter, you are going to have some REALLY unpleasant side effects if you eat the bad foods - it is honestly easier to just avoid the foods than have those side effects!