Coronavirus COVID-19 - Global Health Pandemic #99

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What we are hearing from countries that were first to successfully inoculate most of the population is that, after 6-8 months, people who are double vaccinated are in hospital with severe covid symptoms. In Israel, where the first to be vaccinated were older adults, that demographic group was the first to experience so many "breakthrough" cases that breakthrough was the wrong term. Since then, what is evident is that breakthrough cases occur in people who had been double vaccinated 6-8 months earlier.

Per the CBC article I linked in comment #841, the "rate of infection has been found to be higher in people vaccinated back in January, compared with people who were vaccinated in April ... "In simple words: That protection against infection is waning over time."

This is not a situation where, 8 months after double vaccines, immunity is the same as it was 4 months earlier. This appears to be a situation where people who are double vaccinated can become very ill with the Delta virus 6-8 months after vaccinations. In Israel, 60% of hospitalized covid patients are double vaccinated 6-8 months prior to becoming ill.

"Israel has among the world’s highest levels of vaccination for COVID-19, with 78% of those 12 and older fully vaccinated, the vast majority with the Pfizer vaccine. Yet the country is now logging one of the world’s highest infection rates, with nearly 650 new cases daily per million people. More than half are in fully vaccinated people, underscoring the extraordinary transmissibility of the Delta variant and stoking concerns that the benefits of vaccination ebb over time.
...

What is clear is that “breakthrough” cases are not the rare events the term implies. As of 15 August, 514 Israelis were hospitalized with severe or critical COVID-19, a 31% increase from just 4 days earlier. Of the 514, 59% were fully vaccinated. Of the vaccinated, 87% were 60 or older. “There are so many breakthrough infections that they dominate and most of the hospitalized patients are actually vaccinated,” says Uri Shalit, a bioinformatician at the Israel Institute of Technology (Technion) who has consulted on COVID-19 for the government. “One of the big stories from Israel [is]: ‘Vaccines work, but not well enough.’”
Aug 16, 2021
AAAS

Sep 01, 2021
https://www.cbc.ca/news/world/israel-covid-delta-variant-booster-1.6159472

Sounds like Delta has arrived (I bet we'll see those studies out of Israel soon).

Now the FDA is waffling on allowing us to get booster shots. Talking about reducing it to a microdose. I think I'll get mine before anything else happens.

Also, making rapid antigen testing a thing (cheap and available) needs to be done. I would guess that Delta is behind the uptick in LA county (especially. in the schools, which just started back).

Did Israeli kids just go back to school I wonder? Unvaccinated, asymptomatic Delta carriers interacting maskless with older double vaccinated people is probably not the best scenario.

We do have to disentangle how much is Delta and how much is waning immunity (and what the best predictors of that might be - and what to do!)
 
Let's keep in mind that in UK, it's almost all Astra-Zeneca, whose effects on younger people are still under study and early data seem to show more side effects in kids than for Pfizer or Moderna. Not sure about Johnson/Johnson.

But yes, AZ has a few studies that need more studies to be done. The US studies on Pfizer and Moderna are not presenting those problems, so we're going ahead with 12-17 right now (as well as boosters).

It is not almost all Astra Zeneca in the U.K. Under 40's have been mainly been given Pfizer.
 
I am still trying to figure out why people are so against the vaccine. It is a shot, get it, move on.

Why some people don't want a Covid-19 vaccine

It's not about the shot for many it's about Freedom. Freedom from vaccine mandates and Freedom from government interference.

The Covid vaccine is becoming something of a culture war on social media, with many online commentators claiming that the vaccine hesitant are simply ignorant or selfish. But psychologists who specialise in medical decision-making argue these choices are often the result of many complicating factors that need to be addressed sensitively, if we are to have any hope of reaching population-level immunity.

p09pxfq3.jpg

Most people hesitant about taking the vaccine do not have anti-scientific views like the small minority of anti-vaccine protesters.




 
<modsnip: Quoted post was removed>

Laying in hospital beds some of these anti-vaxxers are begging Doctors for the vaccine, for themselves, and told it's too late.

Also, many anti-vaxxers (from their hospital beds and hooked up to oxygen) go on social media and beg people to get the vaccine.

Vaccine Refusers Don’t Get to Dictate Terms Anymore

People who opt out of shots shouldn’t expect their employers, health insurers, and fellow citizens to accommodate them.
 
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Sounds like Delta has arrived (I bet we'll see those studies out of Israel soon).

Now the FDA is waffling on allowing us to get booster shots. Talking about reducing it to a microdose. I think I'll get mine before anything else happens.

Also, making rapid antigen testing a thing (cheap and available) needs to be done. I would guess that Delta is behind the uptick in LA county (especially. in the schools, which just started back).

Did Israeli kids just go back to school I wonder? Unvaccinated, asymptomatic Delta carriers interacting maskless with older double vaccinated people is probably not the best scenario.

We do have to disentangle how much is Delta and how much is waning immunity (and what the best predictors of that might be - and what to do!)
I already gotten my Moderna booster (my condition is on cdc list). I wasn't sure if should wait or get it, but I decided to get it now-I want my antibodies in tip top shape. Let FDA and CDC waffle, I am boostered.
 
Vaccine will be completely useless after they are infected and in the hospital bed. If they are begging for a vaccine then, they have a complete misunderstanding of what the vaccine is good for.

But when a non-vaccinated person recovers from their Covid infection, testing negative, they are advised to get vaccinated.

How long do they have to wait? Tom Hanks and Rita Wilson recovered from their Covid infections and subsequently, after X amount of time, got their vaccines.
 
But when a non-vaccinated person recovers from their Covid infection, testing negative, they are advised to get vaccinated.

How long do they have to wait? Tom Hanks and Rita Wilson recovered from their Covid infections and subsequently, after X amount of time, got their vaccines.
There has been some conflicting information. The recent study out of Israel suggested that natural immunity is actually very good against delta. People in the US are still advised to get vaccinated after they got infected-not sure how soon after the infection. Initially those infected were told to wait 3 months. Not sure if they are even asked to wait now. But if you are infected and then get vaccinated, supposedly you get even stronger immunity.
 
Chapman University sees COVID-19 outbreak as in-person classes resume

In-person classes are back at Chapman University in Orange County, and more than 200 positive coronavirus cases have been identified among students.

Many roommates are isolating and students are being placed in different locations as school officials are trying to figure out what caused the outbreak.
...
The outbreak comes with 89% of students vaccinated.
...
“I have three roommates, two of them got COVID,” Wharton said. “I think it’s mostly because of the Greek life parties are out and about, orientation week is kind of crazy.”

Student Kris Cruse also complained that social gatherings were a problem.

“People are not wearing masks at any of the parties, and they are all very close, very small spaces usually,” Cruse said.
...
 
Las Vegas store requires proof-of-horse photo to deter customers seeking ivermectin for COVID-19

Store associate Shelly Smith told the outlet that demand for ivermectin began to rise months ago, and that's when she put up a sign warning customers that ivermectin can be dangerous to humans.

She even told an older man visiting the store who explained to her his wife wanted him to be on an "ivermectin plan" that it was not safe for him to take.

"And he says, 'Well, we've been taking it and my only side effect is I can't see in the morning.''

"That's a big side effect, so you probably shouldn't take it," she said.

All this led her to put up a second sign demanding a proof-of-horse photo.

The sign itself says: "Ivermectin will only be sold to horse owners *Must show pic of you and your horse*".
 

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Did Israeli kids just go back to school I wonder? Unvaccinated, asymptomatic Delta carriers interacting maskless with older double vaccinated people is probably not the best scenario.

We do have to disentangle how much is Delta and how much is waning immunity (and what the best predictors of that might be - and what to do!)

Israeli kids just went back to school - on Wednesday (1st September). So, there will be more to their story in the weeks ahead.


Israel reopened its schools on Wednesday after the summer break, but ten per cent of students missed the first day of class.

Of the 2.4 million children due to attend Israeli schools from kindergarten to high school, 250,000 were kept home on the first day of school, said the education ministry.

Some 90,000 of them were infected with COVID-19 or in quarantine, a ministry spokeswoman told AFP.

Another 150,000 were either in cities with high virus rates, or enrolled in classes which did not open due to low vaccination rates.

Israel starts new school year amid surge in coronavirus cases
 
Really interesting watching our situation in Australia. Things we are hearing on TV news this morning (Saturday morning here).

NSW says its going to open up international travel once they reach a certain vaccinated rate (I think 80% fully vaccinated). There are indications that our country's PM is going to let them. No matter how many community cases they have at the time.

Victoria is saying it is going to introduce vaccine passports. If you don't have one, you don't get into venues. Their Premier is saying he is not going to keep locking down the state to protect the unvaccinated (once there are enough vaccines for everyone).

Waiting to hear the other states weigh into the debate. What would happen with regard to quarantine, etc. If people decide to venture to NSW and then fly out of (and back into) the country.

Overall, I don't think we have hospital capacity for escalating covid cases.
 
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Las Vegas store requires proof-of-horse photo to deter customers seeking ivermectin for COVID-19

Store associate Shelly Smith told the outlet that demand for ivermectin began to rise months ago, and that's when she put up a sign warning customers that ivermectin can be dangerous to humans.

She even told an older man visiting the store who explained to her his wife wanted him to be on an "ivermectin plan" that it was not safe for him to take.

"And he says, 'Well, we've been taking it and my only side effect is I can't see in the morning.''

"That's a big side effect, so you probably shouldn't take it," she said.

All this led her to put up a second sign demanding a proof-of-horse photo.

The sign itself says: "Ivermectin will only be sold to horse owners *Must show pic of you and your horse*".

I protest! I demand my freedom!

All cheekiness aside, there were studies early on, that indicated a beneficial effect from ivermectin. However, the required dose for humans was too high to be safe. Some Latin American countries included ivermectin in their treatment protocols.

But, I am not endorsing horse wormer as a covid treatment or prophylaxis, just saying that this didn't come out of nowhere.

DEFINE_ME
 
I protest! I demand my freedom!

All cheekiness aside, there were studies early on, that indicated a beneficial effect from ivermectin. However, the required dose for humans was too high to be safe. Some Latin American countries included ivermectin in their treatment protocols.

But, I am not endorsing horse wormer as a covid treatment or prophylaxis, just saying that this didn't come out of nowhere.

DEFINE_ME

Ivermectin Uses, Side Effects & Warnings - Drugs.com

What is ivermectin?
Ivermectin is an anti-parasite medication.

Ivermectin is used to treat infections in the body that are caused by certain parasites.

Ivermectin is approved for use in humans to treat intestinal strongyloidiasis and onchocerciasis.

Ivermectin is currently being investigated as a treatment for coronavirus SARS-CoV-2, which is the virus that causes COVID-19. The FDA has not approved ivermectin for use in treating or preventing COVID-19 in humans. The World Health Organization (WHO) recommend not to use ivermectin in patients with COVID-19, except in clinical trials.

Ivermectin explained: Why the so-called 'horse drug' has emerged in COVID fight

Ivermectin is a drug used to treat infections caused by parasites, such as river blindness and intestinal problems caused by roundworms.

Scientists who developed ivermectin won the Nobel Prize in Physiology and Medicine in 2015, when the foundation said the drug “revolutionized therapy for patients suffering from devastating parasitic diseases.”

In fact, the Centers for Disease Control and Prevention recommends refugees coming to the United States from most parts of the world take ivermectin as a “presumptive therapy.”

Is it a horse drug?

Versions of ivermectin are also used to deworm livestock, which has caused confusion and fueled political commentary about the use of the drug.
 
Vaccine side effects: How the first and second dose of Pfizer and Moderna affected our reportersSoraNews24 - MSM Japan

9 Moderna 1 Pfizer, firsthand accounts reveal a wide range of different reactions to each dose.

• Seiji Nakazawa (Moderna)
First vaccination:
Felt fine
View attachment 311160
Second Vaccination: His temperature suddenly rose to about 39 degrees Celsius (102.2 degrees Fahrenheit) that night. He then started trembling with the chills into the next afternoon, when his temperature finally dropped to 38 degrees,
returning to normal on the third day after his vaccination.

• Mr Sato (Moderna)
First vaccination: “The next day, I had a fever of 37.8 degrees, and myalgia continued for three days. One week later, the injection site became red and swollen and turned into the so-called ‘Moderna arm’ (where a red rash appears around the injection site)”.
View attachment 311161
Second vaccination: “The next day, I had a fever of 37.6 degrees. Other than that, there were no symptoms like the first one, and I felt fully recovered by the afternoon on the second day after inoculation”.

• Ikuna Kamezawa (Moderna)
First vaccination: “I had a sore arm for two to three days, but it was okay as long as I didn’t sleep on it”.
View attachment 311162
Second vaccination: “On the second day, I had a fever of about 37.5 degrees. It wasn’t really bad, but I didn’t feel great so I didn’t push it and went to bed early. I slept like a log and woke up the next day with a normal temperature and felt much better by then”.

・ Masanuki Sunakoma (Moderna)
First vaccination: “I had pain at the injection site. Maybe it was because I exercised three days after the inoculation, but four days later I got a 40-degree fever so I went to the doctor and took a PCR test but it came back negative. Symptoms subsided the day after taking an antipyretic, which was six days after inoculation”.
View attachment 311163
Second vaccination: “On the day of inoculation, I had myalgia and drowsiness. However, it only lasted until the afternoon of the second day. I was pretty scared that the side effects would be similar to what I experienced after my first dose, but thankfully, it was nothing compared to the first jab”.

・ Takashi Harada (Pfizer)
First vaccination: “Pain near the injection site continued for two days. The day after the inoculation, I developed a slight fever of 37.3 degrees in the morning, but it wasn’t so bad that I couldn’t move, and it calmed down by the evening. I didn’t take any medicine and felt back to normal on the third day”.
View attachment 311164
Second vaccination: “I woke up in the middle of the night on the day of inoculation with mild chills. I felt less pain near the injection site than the first time. I had a mild headache the next morning, but I took some headache medicine and felt better. There were no major side effects, and the night after the injection, I felt back to normal”.

・ P.K. Sanjun (Moderna)
First vaccination: “No side effects in particular. It hurt when I touched the injection site”.
View attachment 311165
Second vaccination: “Fever continued all day the day after the jab. The day after that, the fever subsided, but I had a headache”.

・ Yuichiro Wasai (Moderna)
First vaccination: “Immediately after the vaccination, I felt a tingling pain. The next day, in addition to a painful arm, I also felt tired. Two days after inoculation, the fatigue disappeared, and three days after inoculation, the pain in my arm disappeared”.
View attachment 311166
Second vaccination: “Approximately three hours after the inoculation, my arm hurt and I couldn’t raise it. The next day I had a fever, headache, and malaise. My body temperature only rose to about 37 degrees, but I was in bed all day. The next morning (two days after inoculation), the symptoms of fever, headache, and malaise had almost subsided, and the next day (three days after inoculation), the pain in my arm had pretty much disappeared”.

・ Go Hatori (Moderna)
First vaccination: “The injection site was swollen and painful but it was back to normal in about two days”.
View attachment 311167
Second vaccination: “I felt sluggish on the day of inoculation and throughout the next day. I had a nightmare on the night of the first day, where I dreamed that Masanuki was a last boss in a video game, but I was fine after that and I didn’t have any fever”.

・ Ahiruneko (Moderna)
First vaccination: “Immediately after the inoculation, the pain started. I couldn’t raise my arm, and I couldn’t hold heavy objects for about two days”.
View attachment 311168
Second vaccination: “A fever began to appear in the morning after the inoculation, and even after taking an antipyretic, I had a high fever in the 38-degree range, with chills and joint pain. It felt like the flu but I had an appetite and I recovered the day afterwards”.

・ Kawarano (Moderna)
First vaccination: “There was a dull pain when I tried to raise my arm on the day. The next day, there was pain at tNakazawaction site and my entire arm felt heavy. It was considerably lighter on the third day, though, and there was no swelling. I had a 38-degree fever from around the 27-hour mark through to the 81-hour mark but I slept during that time and I took an antipyretic twice”.
View attachment 311169
Second vaccination: “There were considerably less side effects than the first time. This time, the injection site became slightly red. The fever came earlier than the first time, around 12 hours later, when my temperature rose to 37.5 degrees, before peaking at 38.6 degrees. The fever lasted for around 72 hours, but it was easier than the first time, and on the third day I was able to get back to work.”
I didn't feel squat with either dose of the Moderna and I'm not sure that's a good thing.
 
Ivermectin Uses, Side Effects & Warnings - Drugs.com

What is ivermectin?
Ivermectin is an anti-parasite medication.

Ivermectin is used to treat infections in the body that are caused by certain parasites.

Ivermectin is approved for use in humans to treat intestinal strongyloidiasis and onchocerciasis.

Ivermectin is currently being investigated as a treatment for coronavirus SARS-CoV-2, which is the virus that causes COVID-19. The FDA has not approved ivermectin for use in treating or preventing COVID-19 in humans. The World Health Organization (WHO) recommend not to use ivermectin in patients with COVID-19, except in clinical trials.

Ivermectin explained: Why the so-called 'horse drug' has emerged in COVID fight

Ivermectin is a drug used to treat infections caused by parasites, such as river blindness and intestinal problems caused by roundworms.

Scientists who developed ivermectin won the Nobel Prize in Physiology and Medicine in 2015, when the foundation said the drug “revolutionized therapy for patients suffering from devastating parasitic diseases.”

In fact, the Centers for Disease Control and Prevention recommends refugees coming to the United States from most parts of the world take ivermectin as a “presumptive therapy.”

Is it a horse drug?

Versions of ivermectin are also used to deworm livestock, which has caused confusion and fueled political commentary about the use of the drug.

A bit more info about ivermectin:
  • Different forms of ivermectin are used to treat parasites, such as intestinal worms or lice, in both animals and humans. But the livestock form of the drug should never be used on humans, and parasites are not the same as viruses. COVID-19 is caused by a virus.
  • The largest study in favour of ivermectin as a COVID-19 treatment was retracted after concerns about data fabrication, plagiarism and ethical breaches. No clinical studies have proven whether ivermectin can slow or stop the novel coronavirus from growing in human cells.
https://www.cbc.ca/news/canada/calgary/alberta-covid-coronavirus-september-3-1.6163660
 
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