Homicide detectives are investigating jailed stripper Robyn Lindholm as a serial killer responsible for up to three murders.

Fairfax Media understands Lindholm, 42, who was jailed in December for 25 years for organising the murder of her former lover Wayne Amey, is about to be charged with murdering missing standover man George Teazis, also known as Templeton, in 2005.

Lindholm had been in a volatile, six-year relationship with Teazis and was living with him and his son in Reservoir when the 38-year-old went missing.

When police revealed the disappearance was being treated as suspicious in 2005, Lindholm made an emotional plea for information about her missing fiance.

She said her partner of more than six years had left home between midnight and 1.30am on May 3, while she was out with a girlfriend.

Lindholm also said she received a text message from Templeton at 2.40am suggesting he might need to be picked up after an issue had arisen but that he'd failed to tell her where he was.