If the eye with the coloboma is very small (microphthalmia), other follow-ups may be needed. Conformers and expanders may be used to help support the face and encourage the eye socket to grow. Children may also be fitted for a prosthetic (artificial) eye to improve appearance. As the face develops, new conformers will need to be made.
http://www.nei.nih.gov/health/coloboma/coloboma.asp#15
Colored contact lenses that make the black part of the eye (pupil) round.
Surgery to make the pupil rounder. This procedure pulls and sutures together the lower edges of the iris.
Treating any complications that might arise from a retinal coloboma later in life, such as the growth of new blood vessels at the back of the eye (neovascularization) and/or retinal detachment.